Cordyceps sinensis.
Ophiocordyceps sinensis
Révisé médicalement par Dr. Irvine Russell, M.D.
Ophiocordyceps sinensis (formerly Cordyceps sinensis) is an entomopathogenic ascomycete fungus of the family Ophiocordycipitaceae that parasitizes larvae of ghost moths (Thitarodes/Hepialus spp.) in the alpine grasslands of the Tibetan Plateau and Himalayan regions at elevations of 3,000–5,000 meters. The fungus infects the larva, mummifies it underground, and produces a slender, dark brown stroma (4–10 cm) that emerges from the host's head in spring. Known as Dong Chong Xia Cao ('winter worm, summer grass') in Chinese and Yartsa Gunbu in Tibetan, it is one of the most expensive biological commodities on Earth, with premium specimens commanding $20,000–$100,000+ per kilogram. Unlike the commercially cultivated Cordyceps militaris (which produces cordycepin abundantly), wild O. sinensis contains lower cordycepin concentrations but a unique profile of adenosine, cordycepic acid (D-mannitol), polysaccharides, and sterols that have been valued in Traditional Chinese and Tibetan Medicine for over 1,500 years.
#27
Classement de popularité
Extensive
Niveau de recherche
3
Références
5
Composés clés
Cordycepin
Board-Certified Physician · Medical Reviewer · Dernière révision 25 février 2026
APERÇU SCIENTIFIQUE.
Niveau de preuve: A
Cordyceps sinensis a fait l'objet d'études approfondies tant en recherche préclinique que clinique. Plusieurs essais humains ont étudié ses bienfaits potentiels.
Point clé
Cordyceps sinensis — now officially classified as Ophiocordyceps sinensis — is the original, wild Cordyceps species that has been revered in Tibetan and Chinese medicine for over 1,500 years. It is...
Usage traditionnel
Cordyceps sinensis est utilisé dans les systèmes de médecine traditionnelle depuis des siècles, notamment dans la Médecine Traditionnelle Chinoise (MTC) et d'autres pratiques de guérison asiatiques.
Contexte historique: L'usage traditionnel ne garantit ni l'efficacité ni la sécurité. La recherche moderne est en cours pour valider les allégations traditionnelles.
Cordyceps sinensis — now officially classified as Ophiocordyceps sinensis — is the original, wild Cordyceps species that has been revered in Tibetan and Chinese medicine for over 1,500 years. It is fundamentally different from the Cordyceps militaris already covered on this site, and understanding the distinction matters if you are an informed consumer. While C. militaris is commercially cultivated, affordable, and rich in cordycepin, O. sinensis is wild-harvested from the Tibetan Plateau, extraordinarily rare, and commands prices that can exceed $20,000 per kilogram — making it one of the most expensive biological materials on Earth.
The life cycle of this fungus is both fascinating and macabre. It infects the larvae of ghost moths living underground in high-altitude Tibetan grasslands (3,000–5,000 meters elevation). The fungus slowly consumes the larva from the inside, mummifies it, and then in spring sends up a slender, finger-like fruiting body from the dead caterpillar's head. Tibetan herders call it Yartsa Gunbu — "winter worm, summer grass" — and its harvest each spring is a major economic event for rural Tibetan communities.
In Traditional Chinese Medicine, Cordyceps sinensis is classified as a tonic for the kidneys and lungs. It has been used to support respiratory health, enhance vitality and stamina, improve sexual function, and promote longevity. The Chinese national women's running team famously attributed their record-breaking performances in the 1993 Chinese National Games partly to Cordyceps supplementation, though this claim remains debated. What is not debated is the mushroom's deep cultural significance — it has been a prized gift and status symbol in Chinese culture for centuries.
Here is the critical consumer distinction: most "Cordyceps" supplements on the market today use cultivated C. militaris, not wild O. sinensis. This is not necessarily a bad thing — C. militaris actually contains significantly more cordycepin (up to 90 times more) than wild O. sinensis. However, O. sinensis has a unique chemical profile including specific polysaccharides, sterols, and adenosine that differ from C. militaris. Products claiming to contain wild Cordyceps sinensis at affordable prices should be viewed with skepticism, as the raw material alone costs thousands of dollars per kilogram.
Authentic O. sinensis supplements are available from premium Chinese medicine suppliers, typically at significantly higher prices than C. militaris products. Some products use CS-4, a cultivated mycelium strain of O. sinensis grown through liquid fermentation, which offers a more affordable alternative while maintaining some of the original species' chemical profile. Typical dosages of CS-4 range from 1,000 mg to 3,000 mg per day.
For most consumers seeking Cordyceps benefits — energy, athletic performance, endurance — cultivated C. militaris is the practical and evidence-based choice. O. sinensis is most relevant for those specifically interested in traditional Chinese medicine formulations, the unique chemical profile of the wild species, or the cultural and historical significance of the original Cordyceps. Both species have legitimate health applications, but they are distinct products with different chemical profiles, price points, and evidence bases.
Cordyceps sinensis Posologie
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Révisé médicalement par
Board-Certified Physician · Medical Reviewer
Board-certified physician affiliated with UC Irvine, the Gavin Herbert Eye Institute, and the UCI School of Medicine. Dr. Russell reviews all mushroom encyclopedia entries for scientific accuracy, ensuring claims are supported by peer-reviewed research.
Last reviewed: 25 février 2026
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